Biochemical and Mechanical Characterization of Nereis Worm Jaws

Biochemical and Mechanical Characterization of Nereis Worm Jaws

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The molecular composition of the jaw is also addressed. Protein comprises aˆ¼90% of the jaw mass; amino acid analysis indicates that histidine is increased in the hardened, Zn-rich tip. The major protein component in Nereid jaw extracts is purified and characterized by partial peptide mapping and isolation of a partial clone from a jaw pulp cDNA library. Nvjp-1 is a 38 kDa glycine- histidine-rich protein and is believed to be the principle structural protein in the hardened jaw tip. The effects of selected environmental factors on Nvjp-1 structure and assembly are described. Transition from low to high pH is accompanied by changes in secondary structure and a significant molecular elongation. Furthermore, exposure to transition metals, notably Zn and Cu, results in the formation of amyloid-like fibers at high pH.Dionex Corporation Instructor - Western Region (US) 2001-2002 Responsible for instruction of training courses: Principles of Chromatography, HPLC Maintenance and Troubleshooting, Peaknet Operation (proprietary software). Authoredanbsp;...


Title:Biochemical and Mechanical Characterization of Nereis Worm Jaws
Author: Christopher C. Broomell
Publisher:ProQuest - 2008
ISBN-13:

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